TWO evacuation centres have been activated as the region is hit with flooding a second time.
It comes exactly a month after the region was inundated with water during the Australia Day weekend.
South Burnett Regional Council Mayor Wayne Kratzmann said public safety was now the council's main concern.
"We have quite a few people at Kingaroy Town Hall's reception area and about 15 at the South Burnett PCYC in Murgon," he said.
"And we have quite a few other evacuation centres on standby in Nanango and other areas ready to activate if they are needed."
Cr Kratzmann said people in Byee and Brooklands have been evacuated.
He said the road between Kingaroy and Nanango was still open, with SES crews monitoring the situation.
"You can get to Brisbane via Toowoomba at the moment, but not through Esk, Kilcoy or Gympie," he said.
"Most of our major roads have been closed and we are urging people to stay put unless it's an emergency."
Krebs Bridge near Murgon is currently closed to all vehicles and as at 4.15pm about 70 roads in the South Burnett have been closed.
Up in the North Burnett Monto has recorded more than 90mm today, with reports of five people being rescued.
There have been multiple road closures across the central and north Burnett, with the Burnett Hwy closed between Ban Ban Springs and Gayndah.
To monitor river conditions log onto www.bom.gov.au/cgi-bin/wrap_fwo.pl?IDQ60288.html.