49ers bad luck continues after losing key player to injury

THE news has gone from bad to worse for the San Francisco 49ers ahead of its final regular season game against Arizona.

After being thrashed 42-13 by Seattle last week, the biggest loss under coach Jim Harbaugh, the 49ers have lost wide receiver Mario Mannigham to a season-ending knee injury.

Just this month the team has also lost running back Kendall Hunter to an torn Achilles and wide receiver Kyle Williams to an ACL.

Topics:  nfl san francisco 49ers

Top team wins gong

WINNER WINNER: A team of about 50 health workers from Ipswich won the National Stroke Foundation award for their awareness campaign.

National Stroke Week awareness campaign big success

Unemployment rising in Ipswich

LNP claim 100 jobs have been lost from the region in the past month

Storms on horizon for Ipswich today

Storms lash Ipswich

Showers also possible on Saturday

Local Partners

Workmates honour crash victim with tribute

UPDATE: Tanya Lyell is being remembered as a young mother dedicated to her family and work as the town she called home mourns its loss.

Things to do this weekend

ON STAGE: Dragon play the Ipswich Civic Centre tonight.

See an Oz rock icon, take in a play, or visit a musuem

WATCH: NASA space station is live, see the view from above

In this picture taken from NASA's International Space Station from April 2015, the SpaceX Dragon is captured with the 57.7-foot-long Canadarm2 robotic arm before its installation to the Harmony module.

See the world from a new perspective as space station passes Rocky

Artist feeds us pop straight from heart

FEED THE BEAST: Singer-songwriter Emma Dean is this week's featured artist.

Emerge's Calen Le Couteur recently caught up with Emma Dean

Orlando Bloom 'buried' Katy Perry in birthday flowers

Orlando Bloom "buried" Katy Perry in flowers for her birthday

MacBook fires up: New "touchbar" will include emojis

COULD emojis help the MacBook again deliver a laptop revolution?

Angus T. Jones got miserable on Two and a Half Men

Child star's misery while shooting 'Two and a Half Men'

Bachelorette shock: "This isn't how it's supposed to go!"

Georgia Love pictured in a scene from The Bachelorette finale.

GEORGIA chooses Lee and leaves Matty J heartbroken.

Radio presenter's shocking joke about Dreamworld victims

Images from the scene after four people died on a ride at Dreamworld at the Gold Coast

Radio host taken off air after tactless Dreamworld joke

Things to do this weekend

ON STAGE: Dragon play the Ipswich Civic Centre tonight.

See an Oz rock icon, take in a play, or visit a musuem

Want to own one of Australia's best restaurants?

TOP GONG: Mooloolaba Spice Bar has been named in TripAdvisor's Top 10 Australian restaurants for 2016.

Here's your chance to pick up one of the Coast's favourite eateries

Tough times in CBD: Woolies says goodbye Ipswich

Woolworths in the Ipswich Mall.Photo: Rob Williams / The Queensland Times

The last day of trading will be January 1

Is Woolworths departure good news for Ipswich CBD?

Artist impression of the Ipswich Mall for the rejuvenation project to be undertaken by Ipswich City Properties

Council is on track to release a detailed plan before December

Look at me! Kath and Kim home up for sale

Kath and Kim from the iconic Aussie TV series.

'Crack open the Baileys and grab a box of BBQ Shapes'

How to fit 100,000 new homes on the Coast

Property, real estate, housing, suburb,  August 2016

Fitting 2m extra people in south-east Qld in 25 years a balance

Hinterland horse stud passed in for $8.25 million

UNREAL: This Maleny estate is incredible.

12-bedroom hinterland horse stud still available